6β-hydroxyipolamiide of Stachytarpheta jamaicensis Leaves

Yuliana Yuliana, Fithrotul Auwaliyah, Sri Fatmawati

Abstract


Stachytarpheta jamaicensis is one species of Verbenaceae family that is used as a traditional medicine. 6β-hydroxyipolamiide is a natural occuring compound that was successfully isolated from S. jamaicensis leaves. The identification of compound was analyzed by using UV-Vis, Infra-Red (IR) spectrophotometry and Nuclear Magnetic Resonance (NMR) spectrometry. This is the first report that the compound has isolated from this plant.

Keywords


6β-hydroxyipolamiide, Stachytarpheta jamaicensis, isolation

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References


Lembaga Ilmu Pengetahuan Indonesia, “Status kekinian keanekaragaman hayati Indonesia,” Indonesia, 2014.

S. Facciola, Cornucopia II. Kampong Publication-California, 1998.

G. Arumugam, P. Manjula, and N. Paari, “A review: Anti diabetic medicinal plants used for diabetes mellitus,” J. Acute Dis., pp. 196–200, 2013.

A. Imran et al., “Thymoquinone: A novel strategy to combat cancer: A review,” Biomed. Pharmacother., vol. 106, pp. 390–402, 2018.

Yuliana and S. Fatmawati, “Senyawa Metabolit Sekunder dan Aspek Farmakologi Alocasia Macrorrhizos,” Akta Kim. Indones., vol. 3, pp. 141–158, 2018.

M. Mamun-or-Rashid, H. Shamim, K. H. Naim, S. Biplab, Asharafuzzaman, and S. Monokesh, “A review on medicinal plants with antidiabetic activity,” J. Pharmacogn. Phytochem., vol. 3, pp. 149–159, 2014.

M. Liew and Y. K. Young, “Stachytarpheta jamaicensis (L.) Vahl: from traditional usage to pharmacological evidence,” Evidence-Based Complement. Altern. Med., pp. 1–7, 2016.

M. Kaaiakamanu and J. K. Akina, Hawaiian herbs of medicinal value. University Press of The pasific Honolulu-Hawaii, 2003.

N. Liang and D. Kitts, “Antioxidant property of coffee components: Assessment of methods that define mechanisms of action,” Molecules, vol. 19, pp. 19181–19208, 2014.

M. Rahmatullah, S. A. R. Jahan, H. M. S. Hossan, and T. Rahman, “Folk Medicinal Uses of Verbenaceae Family Plants in Bangladesh,” African J. Tradit. Complement Altern. Med., pp. 53–65, 2011.

O. Adedeji, “Palynology of the Genus Stachytarpheta Vahl. (Verbenaceae),” Not. Sci. Biol., vol. 2, pp. 27–33, 2010.

M. . Sulaiman, Z. A. Zakaria, H. S. Chiong, S. K. Lai, D. A. Israf, and T.M. Shah, “Antinociceptive and Anti-Inflammatory Effects of Stachytarpheta jamaicensis (L.) Vahl (Verbenaceae) in Experimental Animal Models,” Med. Princ. Pract., vol. 18, pp. 272–279, 2009.

N. A. da Silva, J. K. da Silva, E. H. Andrade, L. M. Carreira, P. J. Sousa, and J.G. Maia, “Essential oil composition and antioxidant capacity of Lippia schomburgkiana,” Nat. Prod. Commun., vol. 4, pp. 1281–1286, 2009.

V. Machumi et al., “Antimicrobial and antiparasitic abietane diterpenoids from the roots of Clerodendrum eriophyllum,” Nat. Prod. Commun., vol. 5, pp. 853–858, 2010.

K. Ruffo, A. Birnie, and B. Tengnas, “Edible Wild Plants of Tanzania,” 2002.

O. Akobundun and C. N. Agyakwa, “A hand book on west African weeds,” Nigeria, 1998.

S. Liang and M. G. Gilbert, “Verbenaceae,” Flora of China, vol. 17, pp. 1–49, 1994.

F. Nascimento, L. Juliana, C. F. Paulo, and L. S. Giuliana, “Antibacterial activity of plant extracts and phytochemicals on antibiotic-resistant bacteria,” Brazilian J. Microbiol., vol. 31, pp. 247–256, 2000.

R. Dewoto, “Pengembangan Obat Tradisional Indonesia Menjadi Fitofarmaka,” Maj. Kedokt. Indones., vol. 57, no. 7, 2007.

N. Malviya, S. Jain, and S. Malviya, “Antidiabetic potential of medicinal plants,” Acta Pol. Pharm. Drug Res., vol. 67, pp. 113–118, 2010.

K. Upadhyay, “Antidiabetic potential of plant natural products: A review,” Int. J. Green Pharm., vol. 10, pp. 96–113, 2016.

L. Rıos and M. C. Recio, “Medicinal plants and antimicrobial activity,” J. Ethnopharmacol., vol. 100, pp. 80–84, 2005.

M. Cowan, “Plant products as antimicrobial agents,” Clin. Microbiol. Rev., vol. 12, pp. 1564–1567, 1999.

R.Sivaranjani, K. Ramakrishnan, and G. Bhuvaneswari, “Pharmacognostic studies on root of Stachytarpheta jamaicensis,” Int. Lett. Nat. Sci., vol. 8, pp. 100–105, 2014.

O. Silambujanaki, V. Chitra, D. Soni, D. Raju, and M. Sankari, “Hypoglycemic activity of Stachytarpheta indica on streptozotocin induced wistar strain rat,” Int. J. PharmTech Res., vol. 1, pp. 1564–1567, 2009.

R. Sahoo, R. R. Dash, and S. Bhatnagar, “Phytochemical screening and bioevaluation of medicinal plant Stachytarpheta indica (L.) Vahl.,” Pharmacol. Toxicol. Res., vol. 1, pp. 1–5, 2014.

G. Christian, U. P. Monday, and U. E. Charles, “Antibacterial potential of the methanol stem bark extract of Stachytarpheta indica,” Asian J. Med. Sci., vol. 4, pp. 5–10, 2013.

S. Olalode, O. O. Ogunmola, S. E. Kuyooro, and O. O. Abiona, “Stachytarpheta jamaicensis leaf extract: Chemical composition, antioxidant, anti-arthritic, anti-inflammatory and bactericidal potentials,” J. Sci. Innov. Res., vol. 6, pp. 119–125, 2017.

S. Schapoval, de V. M. R. Winter, and C. G. Chaves, “Antiinflammatory and antinociceptive activities of extracts and isolated compounds from Stachytarpheta cayennensis,” J. Etnopharmacology, vol. 60, pp. 53–59, 1998.

C. Penido et al., “Anti-inflammatory and anti-ulcerogenic properties of Stachytarpheta cayennensis (L Rich) Vahl.,” J. Ethnopharmacol., vol. 104, pp. 225–233, 2006.

A. C. Adebajo et al., “Hypoglycemic constituens of Stachytarpheta cayyenensis leaf,” Planta Med., vol. 73, pp. 241–250, 2007.

C. Pandian, A. Srinivasan, and I. C. Pelapolu, “Evaluation of wound healing activity of hydroalcoholic extract of leaves of Stachytarpheta jamaicensis in streptozotocin induced diabetic rats,” Der Pharm. Lett., vol. 5, pp. 193–200, 2003.

R. M.Hassan, Y. N.Eizzatie, and N. Samsulrizal, “Hypoglycemic and Antioxidant activities of Stachytarpheta jamaicensis ethanolic leaves extract on alloxan-induced diabetic sprague dawley rats,” Biotechnol. An Indian J., vol. 9, pp. 423–428, 2014.

C. Oyoke, P. A. Akah, C. O. Okoli, A. C. Ezike, and F. N. Mbaoji, “Antimicrobial and antispasmodic activity of leaf extract and fractions of Stachytarpheta cayennensis,” Asian Pac. J. Trop. Med., pp. 189–192, 2010.

A. D. Souza et al., “Evaluation of antimicrobial, antioxidant and phototoxic activities of extracts and isolated compounds from Stachytarpheta cayennensis (Rich.) Vahl, Verbenaceae,” Brazilian J. Pharmacogn., vol. 20, pp. 922–928, 2010.

V. Enwuru, S. O. Ogbonnia, F. Nkemehule, F. Enwuru, and O. Tolani, “Evaluation of antibacterial activity and acute toxicity of the hydroethanolic extract of Stachytarpheta angustifolia (Mill) Vahl,” African J. Biotechnol., vol. 7, pp. 1740–1744, 2008.

S. Silva, Y. Suzuki, A. P. Moreira, N. R. B. Raposo, T. M. A. Alves, and L. F. Viccini, “Stachytarpheta gesnerioides Cham.: chemical composition of hexane fraction and essential oil, antioxidant and antimicrobial activities,” Boletín Latinoam. Caribe Plantas Med. Aromáticas, vol. 11, pp. 542–548, 2012.

S. Sasidharan, L. Y. Latha, Z. Zuraini, S. Sangetha, and L. Shirley, “Antidiarrheal and antimicrobial activities of Stachytarpheta jamaicensis,” Indian J. Pharmacol., vol. 39, pp. 245–248, 2007.

N. Burkill, The useful plants of west tropical Africa Royal Botanic Gardens. 1985.

B. Alice et al., “Screening of plants used in south Brazilian folk medicine,” J. Ethnopharmacol., vol. 35, pp. 165–171, 1991.

R. D. Robinson, L. A. Williams, J. F. Lindo, and S. I. Terry, “Inactivation of Strongyloides stercoralis filariform larvae in vitro by six Jamaican plant extracts and three commercial anthelmintics,” West Indian Med. J., vol. 39, pp. 213–217, 1990.

E. Almeida, M. G. Karnikowski, R. Foleto, and B. Baldisserotto, “Analysis of antidiarrhoeic effect of plants used in popular medicine,” Rev. Saude Publica, vol. 29, pp. 428–433, 1995.

R. Irchhaiya et al., “Metabolites in plants and its classification,” World J. Pharm. Pharm. Sci., vol. 4, pp. 287–305, 2014.

P. Anulika, E. O. Ignatius, E. S. Raymond, O.-I. Osasere, and H. A. Abiola, “The chemistry of natural product: Plant secondary metabolites,” Int. J. Technol. Enhanc. Emerg. Eng. Res., vol. 4, 2016.

K. Ramakrishnan and R. Sivaranjani, “Pharmacognostical and phytochemical studies on stem of Stachytarpheta jamaicensis (L) Vahl.,” Int. Res. J. Pharm., vol. 4, pp. 44–47, 2013.

M. Idu, E. K. I. Omogbai, G. E. Aghimien, F. Amaechina, O. Timothy, and S. E. Omongho, “Preliminary phytochemistry, antimicrobial properties and acute toxicity of Stachytarpheta jamaicensis (L.) Vahl. Leaves,” Trends Med. Res., vol. 2, pp. 193–198, 2007.

D. E. Okwu and O. N. Ohenhen, “Isolation, characterization and antibacterial activity of lanostane triterpenoid from the leaves of Stachyterpheta jamaicensis Linn Vahl.,” Der Chem. Sin., vol. 1, pp. 6–14, 2009.

D. E. Okwu and O. N. Ohenhen, “Isolation and characterization of Steroidal Glycosides from the leaves of Stachytarpheta Jamaicensis Linn Vahl.,” Der Chem. Sin., vol. 1, pp. 6–14, 2010.

S. Raj, M. Berthomier, M. A. Babu, S. Karthlkeyan, A. Sivakumar, and K. M. Gothandam, “Antioxidant, Antibacerial and Anti-Proliferative Activity and Phytochemical Analysis of Selected Medical Plants from Dasapushpam of Kerala,” Int. J. Pharm. Sci., vol. 23, pp. 172–179, 2013.

B. Harbone., Metode Fitokimia: Penentuan cara modern menganalisis tumbuhan. Bandung: ITB Press, 1987.

N. Stieger and W. Liebenberg, “Recrystallization of Active Pharmaceutical Ingredients,” 2012.

A. Pandey and S. Tripathi, “Concept of standardization, extraction and pre phytochemical screening strategies for herbal drug,” J. Pharmacogn. Phytochem., vol. 2, pp. 115–119, 2014.

F. S. Sibul, D. Z. Orcic, E. Svircev, and N. M. Mimica-Dukic, “Optimization of extraction conditions for secondary biomolecules from various plant species,” Hem. Ind., vol. 70, pp. 473–483, 2016.

Dachriyanus, “Analisis Struktur Senyawa Organik Secara Spektroskopi,” Padang, 2004.

Suyatno, Penentuan Struktur Molekul Senyawa Organik dengan Metode Spektroskopi. Surabaya: Unesa University Press, 2016.

E. Fukushi, “Advanced NMR approaches for a detailed structure analysis of natural products,” Biosci. Biotechnol. Biochem., vol. 70, pp. 1803–1812, 2006.

E. Caytan, R. Ligny, J.-F. Carpentier, and S. M. Guillaume, “Evaluation of band-selective HSQC and HMBC: methodological validation on the cyclosporin cyclic peptide and application for poly(3-hydroxyalkanoate)s stereoregularity determination,” Polymers (Basel)., vol. 10, pp. 1–15, 2018.

M. Kock, B. Reif, W. Fenical, and C. Griesinger, “Differentiation of HMBC two- and three-bond correlations: a method to simplify the structure determination of natural products,” Tetrahedron Lett., vol. 37, pp. 363–366, 1996.

C. D. Luca, M. Guiso, and C. Martinot, “6β-Hidroksipolamiide, an iridoid glucoside from Stachytarpheta mutabilis,” Phytochemistry, vol. 22, pp. 1185–1187, 1983.




DOI: http://dx.doi.org/10.12962/j20882033.v30i3.5408

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